Punctal occlusion is safe and efficient for the treatment of keratoconjunctivitis sicca in patients with ocular GvHD

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Diagnostic tests in patients with symptoms of keratoconjunctivitis sicca.

We compared the relative value of the tear film breakup time, Schirmer test, lactoferrin immunologic assay and rose bengal staining in 156 patients with varying severity of symptoms characteristic of keratoconjunctivitis sicca and in 39 controls. Statistical analysis showed that in patients with minimal ocular irritation the Schirmer test in combination with the lactoferrin immunologic assay pr...

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Tear film osmolarity and ocular surface disease in two rabbit models for keratoconjunctivitis sicca.

We report the natural history of keratoconjunctivitis sicca (KCS) in two rabbit models. The first one (full KCS model) was created by closing the lacrimal gland excretory duct, and removing the nictitating membrane and harderian gland. We created the second one (lacrimal gland duct only [LGDO]-KCS model) by closing the lacrimal gland excretory duct. Although tear film osmolarity was abnormally ...

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ژورنال

عنوان ژورنال: Bone Marrow Transplantation

سال: 2011

ISSN: 0268-3369,1476-5365

DOI: 10.1038/bmt.2011.205